Interactions of nucleic acids with fluorescent dyes: spectral properties of condensed complexes.
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چکیده
منابع مشابه
Electrochemical and Spectroscopic Studies of Interactions of Mn(III) Complexes with Nucleic Bases and Nucleosides
The complexes of Mn(OAc)3 and/or Mn(acac)3 with nucleic bases and nucleosides (adenine, guanine, xanthine, adenosine and guanosine) have been synthesized in nonaqueous solution. Polarographic and spectroscopic (IR and Visible) methods have been used to establish the active site(s) on the imidazole and pyrimidine rings in the nucleic bases and nucleosides for the intera...
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A new modular approach to the design and discovery of fluorophores and sensors built on a DNA backbone is described. Fluorescent designer nucleosides are synthesized into short oligomers; their close interactions results in highly efficient reporters with properties not seen in standard fluorophores. Applications in sensing of molecules, ions, and enzymes in water and in the vapor phase are des...
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The absorption and fluorescence spectra of some basic dyes were measured in the pre sence of large excess of adenosine or nucleic acids. The visible absorption band of dye shifts to longer wavelengths than that in free dye solution. The fluorescence spectral shape and peak posi tion remain unchanged on the addition of nucleoside or nucleic acid, while the fluorescence inten sity is enhanced ...
متن کاملStable fluorescent complexes of double-stranded DNA with bis-intercalating asymmetric cyanine dyes: properties and applications.
The synthesis, proof of structure, and the absorption and fluorescence properties of two new unsymmetrical cyanine dyes, thiazole orange dimer (TOTO; 1,1'-(4,4,7,7-tetramethyl-4,7- diazaundecamethylene)-bis-4-[3-methyl-2,3-dihydro-(benzo-1,3-thiaz ole)-2- methylidene]-quinolinium tetraiodide) and oxazole yellow dimer (YOYO; an analogue of TOTO with a benzo-1,3-oxazole in place of the benzo-1,3-...
متن کاملelectrochemical and spectroscopic studies of interactions of mn(iii) complexes with nucleic bases and nucleosides
the complexes of mn(oac)3 and/or mn(acac)3 with nucleic bases and nucleosides (adenine, guanine, xanthine, adenosine and guanosine) have been synthesized in nonaqueous solution. polarographic and spectroscopic (ir and visible) methods have been used to establish the active site(s) on the imidazole and pyrimidine rings in the nucleic bases and nucleosides for the interaction with the mn(iii) com...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1990
ISSN: 0022-1554,1551-5044
DOI: 10.1177/38.9.1696951